{"id":2759,"date":"2019-11-19T16:04:09","date_gmt":"2019-11-19T21:04:09","guid":{"rendered":"https:\/\/parkinsonpost.com\/?p=2759"},"modified":"2019-11-19T16:04:09","modified_gmt":"2019-11-19T21:04:09","slug":"putting-saliva-to-good-use","status":"publish","type":"post","link":"https:\/\/archiveparkinson.thedev.ca\/fr\/putting-saliva-to-good-use\/","title":{"rendered":"Putting saliva to good use"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignright size-large\"><img loading=\"lazy\" width=\"200\" height=\"200\" src=\"https:\/\/parkinsonpost.com\/wp-content\/uploads\/02-Gornitsky.jpg\" alt=\"\" class=\"wp-image-2761\" srcset=\"https:\/\/archiveparkinson.thedev.ca\/wp-content\/uploads\/02-Gornitsky.jpg 200w, https:\/\/archiveparkinson.thedev.ca\/wp-content\/uploads\/02-Gornitsky-150x150.jpg 150w, https:\/\/archiveparkinson.thedev.ca\/wp-content\/uploads\/02-Gornitsky-100x100.jpg 100w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><figcaption>Dr. Mervyn Gornitsky<br \/>Professor Emeritus<br \/>McGill University<\/figcaption><\/figure>\n<\/div>\n<p>If researchers could find a non-invasive, physiological tool to diagnose Parkinson\u2019s disease, it might be easier to start treatment earlier. At McGill University, <strong>Dr. Mervyn Gornitsky<\/strong> believes he has done just that\u2014by measuring the quantity of a protein called heme oxygenase-1 (HO-1) in samples of the saliva of people who have Parkinson\u2019s. Gornitsky, an oral surgeon, is using his biobank of 4,000 saliva samples to confirm the test\u2019s ability to determine the presence of Parkinson\u2019s in people who are in the early stages of the disease, even before they show tremors, stiffness or other motor control symptoms.<\/p>\n<p>As an oral surgeon in Montreal, Dr. Mervyn Gornitsky was constantly surrounded by his patients\u2019 spit.<\/p>\n<p>\u201cHere I was with all of this liquid around me, watching it go down the drain and wondering whether I could use saliva and find out if there\u2019s anything in saliva that could determine disease,\u201d says Gornitsky, a professor emeritus at McGill University.&nbsp;<\/p>\n<p>Today, he is doing just that and has created a biobank of more than 4,000 saliva samples that he\u2019s using to help diagnose Parkinson\u2019s disease, as well as other illnesses. This research project was made possible through a Pilot Project Grant for $49,200 over one year from the Parkinson Canada National Research Program.<\/p>\n<p>\u201cWe found all kinds of things in saliva because it absolutely has many different types of chemicals and materials that are part of your saliva and salivary glands,\u201d he says.<\/p>\n<p>Gornitsky measures the amount of a protein called heme oxygenase-1 (HO-1) in saliva, correlating the quantity of the protein to people in the early stages of Parkinson\u2019s disease.&nbsp;&nbsp;<\/p>\n<p>In an early study, he and his colleagues have already demonstrated that the highest levels of HO-1 are found in the saliva of people in the early stages of Parkinson\u2019s disease.<\/p>\n<p>\u201cWe were the first to use saliva as a biomarker for early Parkinson\u2019s, and that (discovery) was published just recently in <em>Movement Disorders,<\/em> the official journal of the <em>Movement Disorders Society<\/em>,\u201d Gornitsky says.<\/p>\n<p>Now, he\u2019s refining the test to diagnose Parkinson\u2019s even earlier, in people who don\u2019t yet exhibit any of the motor symptoms such as stiffness, tremors or rigidity that plague people in later stages of the illness.&nbsp;&nbsp;<\/p>\n<p>Researchers have already determined that people who\u2019ve lost their sense of smell and\/or have digestion problems or other seemingly unrelated symptoms may go on to develop Parkinson\u2019s. This is the population of people Gornitsky is targeting in his research, as well as those with a family history of the disease.<\/p>\n<p>If those people could be diagnosed early, they could begin taking levodopa right away, or benefit from any new drugs developed to halt Parkinson\u2019s progression.<\/p>\n<p><p>\u201cIf we get people diagnosed early before they have the movement disorder symptoms that normally come with Parkinson\u2019s, then we could delay those movement symptoms to a later date,\u201d Gornitsky says. \u201cIt\u2019s not going to cure the disease but we will maybe be able to get a few years where people will not have the severe Parkinson\u2019s effects.\u201d<\/p>\n<p>Eventually, Gornitsky hopes saliva could be the basis for an easy, inexpensive test that doctors could use to diagnose Parkinson\u2019s right in their offices.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If researchers could find a non-invasive, physiological tool to diagnose Parkinson\u2019s disease, it might be easier to start treatment earlier. &#8230; <a href=\"https:\/\/archiveparkinson.thedev.ca\/fr\/putting-saliva-to-good-use\/\" class=\"more-link\">En savoir plus<\/a><\/p>\n","protected":false},"author":37,"featured_media":2761,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[237],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Putting saliva to good use - Parkinson Canada<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Putting saliva to good use - Parkinson Canada\" \/>\n<meta property=\"og:description\" content=\"If researchers could find a non-invasive, physiological tool to diagnose Parkinson\u2019s disease, it might be easier to start treatment earlier. ... 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